This part of GB/T 31270 specifies the basic requirements on materials, conditions, operation, quality control, data processing and test report of avian acute oral toxicity test and acute feeding toxicity test.
This part applies to avian acute oral toxicity test and acute feeding toxicity test performed for registration of chemical pesticides. It may serve as a reference for other types of pesticides.
This part does not apply to volatile and insoluble chemical pesticides.
2 Terms and definitions
For the purposes of this document, the following terms and definitions apply.
2.1
median lethal dose
dose of the test substance, at which 50% of the test organisms are killed in the acute oral toxicity test, expressed by LD50
Note: the unit is in mg a.i./kg body weight.
2.2
median lethal concentration
concentration of the test substance in the fodder, at which 50% of the test organisms are killed in the acute feeding toxicity test, expressed by LC50
Note: the unit is in mg a.i./kg fodder.
2.3
test substance
substance to be tested
2.4
chemical pesticide
pesticide made from chemical substances through artificial synthesis, some of which are synthetic bionic pesticides made through imitation, structural transformation and innovation by taking the active substances in natural products as the matrix
Synonym: synthetic organic pesticide.
[Definition 2.3.1, NY/T 1667.1-2008]
2.5
technical material
final product consisting of active ingredients and impurities obtained during the manufacturing process, which shall not contain visible foreign substances or any additives, and if necessary, a small amount of stabilizer may be added
[Definition 2.5.1, NY/T 1667.2-2008]
2.6
formulation
product stable in use and made from technical materials (or technical concentrate) of pesticides and auxiliaries
[Definition 2.4, NY/T 1667.2-2008]
2.7
active ingredient; a.i.
biologically active ingredient (with a specific chemical structure) in pesticide products
[Definition 3.1, NY/T 1667.2-2008]
3 Test overview
3.1 Method selection
The avian acute toxicity test can be conducted via oral or feeding, and relevant methods shall be selected according to regulations on pesticide registration management and other regulations.
