Standard No.:	GB/T 36908-2018
Chinese Name:	染料产品中致敏染料的限量和测定
English Name:	Limit and determination of sensitizing dyes in dye products
Professional Classification:	G55 Basic standards and general methods for dye
ICS Classification:	71.100.01 Chemical product synthesis 87.060.10 Pigments and extenders
Issued by:
Issued on:	2018-12-28
Implemented on:	2019-11-01
Status:	VALID
Language:	English
File Format:	PDF
Word Count:	8000 words
Price(USD):	240 (USD)
Delivery:	via email in 1-3 business day

1 Scope

This standard specifies the limit requirements and determination methods for 20 types of sensitizing dyes (see Annex A) in dye products.

This standard is applicable to each dosage form of dye products.

2 Normative references

The following referenced documents are indispensable for the application of this document. For dated references, only the edition cited applies. For undated references, the latest edition of the referenced document (including any amendments) applies.

GB/T 6682-2008 Water for analytical laboratory use - Specification and test methods (ISO 3696: 1987, MOD)
GB/T 8170-2008 Rules of rounding off for numerical values & expression and judgment of limiting values

3 Requirements

The content of all sensitizing dyes (see Annex A) in dye products shall not be greater than 150 mg/kg.

4 Theory

Dissolve out the sensitizing dyes in the dyes with methanol as solvent. Separate and carry out qualitative determination for each sensitizing dye by using the high performance liquid chromatography-diode array detector (HPLC-DAD), and quantify then using the peak area external standard method. Detected and uncertain samples shall be qualitatively determined by liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).